New chapter in my career

Apologies for the radio silence over the past 18 months. My work life took an interesting turn and I’ve been swamped ever since setting up both a new venture capital firm and a new TechBio startup. I’m back blogging now, and from a different perspective – no longer just a retained adviser, interim CBO or board member for startups, but also a startup CEO and venture investor.

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3 Drug Development Principles for Smart SMEs

I was inspired to post this article after someone said to me, “The drug development skills learnt in big pharma translate naturally to the biotech world … you just have a smaller budget”. While the technical skills are essentially the same, I feel strongly that the context and mindset in which they are applied are fundamentally different. This article highlights three ways in which “smart” small/medium-sized enterprises (SMEs) conduct drug development.

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Lessons from Leicester City’s success for Bioscience SMEs

As the 2015–16 English Premier League football season ends, I reflect on the lessons that smaller/medium sized enterprises (SMEs) can learn from Leicester City’s unlikely victory. In addition, to the usual lessons on how an underdog can triumph over much bigger competitors, I explore three other important lessons that are less obvious.

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Root Causes of the Pharmaceutical R&D Productivity Crisis

Root Causes of the Pharmaceutical R&D Productivity Crisis

Why are success rates in pharmaceutical R&D so low? And unlike many other industries where technology has accelerated R&D, why has the productivity trend in pharmaceutical R&D been worsening over the past few decades? As the reasons are not obvious, I thought it would be illuminating to many of my blog readers if I summarized the key findings of the most influential studies and papers investigating the root causes of the pharmaceutical R&D productivity crisis. Full references to all the papers mentioned are provided at the end of this article.

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