Scientists and engineers are inherently resistant to top-down change efforts – they are highly educated and intellectually-strong individuals who “don’t like being told by someone else what to do”. Many change initiatives in scientific and technical organizations have failed to even get off the ground properly. And those that did often stalled or plateaued with few of the planned benefits achieved. Nevertheless, sustainable and valuable change can be achieved by combining the unique characteristics of each organization’s culture, people and business with an appropriate change process for its situation and needs.