I was inspired to post this article after someone said to me, “The drug development skills learnt in big pharma translate naturally to the biotech world … you just have a smaller budget”. While the technical skills are essentially the same, I feel strongly that the context and mindset in which they are applied are fundamentally different. This article highlights three ways in which “smart” small/medium-sized enterprises (SMEs) conduct drug development.Continue reading →
Many new biotechs start off as virtual companies. But at each stage of development, you always end up asking whether you should stay virtual or build your own in-house wet labs. What are the pros and cons of being virtual? And is there a more pragmatic “semi-virtual” approach?Continue reading →
Many research-stage biotechs and other small to medium-sized enterprises (SMEs) prioritize partnerships with Big Partners or in Big Disease Indications without sufficient consideration of other options. But SMEs need to consider other factors when deciding who to partner their assets with and how. As do large pharmas partnering with SMEs
As the 2015–16 English Premier League football season ends, I reflect on the lessons that smaller/medium sized enterprises (SMEs) can learn from Leicester City’s unlikely victory. In addition, to the usual lessons on how an underdog can triumph over much bigger competitors, I explore three other important lessons that are … Continue reading →
Triggered by recently published studies on R&D performance, I have engaged in some interesting discussions over the past few weeks on where to focus productivity improvement efforts. Here in one contiguous article is my take on the key levers for improving productivity in a bioscience R&D organization.
Some interesting findings from an industry study on the operational performance drivers in clinical R&D were published earlier this month, many of them challenging established wisdom. In this article, I comment on these findings and look at their implications for both the big pharmas and especially the smaller biopharma SMEs. … Continue reading →
As six months have now elapsed since its initial publication in the peer-reviewed journal Research-Technology Management (RTM), we reproduce here the full text of the paper authored by myself and Timo Lotta. This paper documents a comprehensive case study of how Orion Pharma’s R&D organization was transformed to implement a … Continue reading →
Partnering assets with large pharmaceutical, diagnostic or medical device multinationals is a critical part of the business model for many small and medium-sized enterprises (SMEs) in the life sciences. But does it make sense for an SME to have a clearly defined partnering strategy or should it be opportunistic?